Born in New Orleans, he is an acclaimed actor, director, and writer known for his work in independent cinema. He gained recognition alongside his brother, Mark, as a pioneer of the mumblecore film movement. His career spans both film and television, with notable acting roles in projects like "Transparent" and "The Chair." He has also directed and produced acclaimed films and series, often exploring themes of family and human relationships. His work is characterized by a focus on authentic storytelling.