Born in Louisville, Kentucky, and raised in Indiana, she initially pursued a career in music, studying at the Chicago Music College. Transitioning to acting, she made her Broadway debut in the 1920s. She became a prominent Hollywood actress in the 1930s and 1940s, known for her versatility in both comedic and dramatic roles. Her notable films include "The Awful Truth," "Love Affair," and "I Remember Mama." Her talent earned her five Academy Award nominations. She later retired from acting and engaged in philanthropy.