"Your Lie in April" is often regarded as one of the saddest anime due to its poignant exploration of themes like love, loss, and the struggles of overcoming trauma. The story follows a piano prodigy, Kōsei Arima, who grapples with the death of his mother and his inability to hear the sound of his own playing. The emotional depth, character development, and tragic elements, particularly involving the character Kaori Miyazono, resonate deeply with viewers. While "saddest" is subjective, it is certainly among the most heart-wrenching anime.

"Your Lie in April" is a coming-of-age anime film that explores themes of love, loss, and the healing power of music. It features emotional and sometimes heavy topics, including mental health issues, grief, and the struggles of young musicians. While it contains moments of sadness and intense emotional situations, it is generally appropriate for older teens and adults. The film emphasizes personal growth and the importance of facing one's emotions, making it a poignant and impactful story rather than inappropriate. Viewer discretion is advised for younger audiences.

There is no Season 2 of "Your Lie in April." The anime is based on the manga by Naoshi Arakawa, which has a complete story. The series aired in 2014 and consists of 22 episodes, concluding the story of Kōsei Arima and Kaori Miyazono. While the anime was well-received and has a significant fanbase, there have been no announcements regarding a continuation or a second season. The story is considered complete as presented in the anime and manga.

In "Your Lie in April," Kaori Miyazono, a talented violinist, struggles with a serious illness that is ultimately revealed to be a terminal condition. Throughout the story, she inspires the protagonist, Kōsei Arima, to rediscover his passion for music. However, despite her vibrant personality and love for life, Kaori's health deteriorates, leading to her hospitalization. In the end, she passes away, leaving Kōsei heartbroken but profoundly changed by her influence and the memories they created together.