Yes, Nolan Ryan famously threw 235 pitches in a game on April 27, 1974, while playing for the California Angels against the Boston Red Sox. This marathon performance is one of the longest outings in Major League Baseball history. Ryan pitched a complete game, striking out 19 batters, although he also allowed 11 hits and walked 4. This event is often highlighted to illustrate Ryan's incredible stamina and durability as a pitcher, solidifying his legacy in baseball.

Yes, David Wells was reportedly hungover during his perfect game on May 17, 1998, while pitching for the New York Yankees against the Minnesota Twins. Wells had celebrated the night before with friends, which led to him feeling less than his best on game day. Despite his state, he managed to throw a perfect game, retiring all 27 batters he faced and achieving one of baseball's rarest feats. His performance that day remains legendary in sports history.

In the context of the movie "The Perfect Game," which is based on the true story of the 1957 Little League team from Monterrey, Mexico, the film does not focus on a specific major league perfect game. However, as of my last update in October 2023, the most recent pitcher to throw a perfect game in Major League Baseball is Félix Hernández, who achieved this feat on August 15, 2012, while playing for the Seattle Mariners against the Tampa Bay Rays. Perfect games are rare and celebrated events in baseball history.

Yes, there has been a 27-strikeout game in Major League Baseball history. This remarkable feat was achieved by Tom Seaver on April 22, 1970, when he struck out all 27 batters he faced in a game. However, it's important to note that this is a theoretical scenario, as no pitcher has ever struck out every single batter in a game under the current rules. The closest real-life instance is the perfect game, where a pitcher retires all 27 batters without allowing a hit or walk, but not all batters struck out.