"The Hitchhiker's Guide to the Galaxy," based on Douglas Adams' novel, follows the misadventures of Arthur Dent, an ordinary human who is whisked away from Earth just before its destruction. The main point of the story is to explore the absurdity of life, the universe, and everything within it, often highlighting the randomness of existence and the importance of humor. The titular guide serves as a comedic, electronic travel book that offers advice and insights on navigating the cosmos, emphasizing the value of curiosity and open-mindedness.

Elon Musk has referenced "The Hitchhiker's Guide to the Galaxy" in relation to his views on space exploration and technology. He appreciates the book's humorous take on the absurdity of life and the universe. Musk has mentioned the phrase "Don't Panic," which is a key motto from the series, emphasizing a calm approach in the face of challenges. His interest in space travel aligns with the book's themes of adventure and exploration beyond Earth.

One of the most famous quotes from "The Hitchhiker's Guide to the Galaxy" is "Don't Panic." This phrase serves as a reassuring mantra throughout the story, emphasizing the importance of staying calm in the face of the absurdities and challenges of life in the universe. The quote is prominently featured in the electronic guidebook that provides information and advice to intergalactic travelers. The book itself, written by Douglas Adams, blends humor, science fiction, and philosophical commentary.

In "The Hitchhiker's Guide to the Galaxy," the number 42 is humorously presented as the "Answer to the Ultimate Question of Life, the Universe, and Everything." However, the actual question itself is unknown, leading to absurdity and confusion. The choice of 42 was made by author Douglas Adams arbitrarily, emphasizing the randomness of existence and the futility of seeking simplistic answers to complex philosophical questions. This has since become a cultural reference symbolizing the search for meaning in life.