The 2016 "Suicide Squad" and the 2021 "The Suicide Squad" are part of the DC Extended Universe (DCEU) but are not directly connected in terms of storyline or character continuity. The 2021 film is a standalone sequel and features some returning characters, like Harley Quinn (Margot Robbie) and Amanda Waller (Viola Davis), but with a new cast and a different tone. Director James Gunn aimed for a fresh take, making it distinct from the earlier film while still existing within the same universe.

Two "Suicide Squad" movies were made to refresh the franchise and explore different storytelling approaches. The original, released in 2016 and directed by David Ayer, received mixed reviews despite box office success. To reinvigorate the series, "The Suicide Squad," directed by James Gunn, was released in 2021. This sequel not only aimed for a more cohesive and humorous tone but also introduced new characters and a fresh narrative style, appealing to both critics and audiences. Each film represents a different vision within the same universe.

"Suicide Squad 2," officially titled "The Suicide Squad," received mixed reviews and struggled at the box office despite critical acclaim. Factors contributing to its underperformance include competition from other films, the impact of the COVID-19 pandemic on theater attendance, and the film's release on HBO Max simultaneously, which may have deterred some from seeing it in theaters. Additionally, the first "Suicide Squad" film's poor reception may have affected audience expectations and interest in the sequel.

As of October 2023, there are two main "Suicide Squad" movies. The first is "Suicide Squad," released in 2016, directed by David Ayer. The second is "The Suicide Squad," released in 2021, directed by James Gunn. While both films feature the same concept of a team of antiheroes undertaking dangerous missions for the government, they differ in tone and style, with the 2021 film being a standalone sequel that introduces new characters and a fresh approach.