As of now, there has been no official announcement regarding a second season of the "Mr. & Mrs. Smith" series, which is a reboot of the 2005 film. The show, starring Donald Glover and Maya Erskine, premiered on Amazon Prime Video in November 2022. Since its release, updates on renewal or cancellation have been limited. For the most accurate and current information, it's best to keep an eye on announcements from Amazon or the show's producers.

"Mr. & Mrs. Smith," released in 2005 and directed by Doug Liman, was a commercial success. Starring Brad Pitt and Angelina Jolie, the film grossed over $478 million worldwide against a budget of approximately $110 million. It received mixed reviews from critics but became popular with audiences, partly due to the chemistry between its leads. Its success contributed to a significant boost in the careers of both actors and helped establish Jolie as a major box office draw. Overall, it is considered a hit.

As of October 2023, there is no season 2 of "Mr. & Mrs. Smith" because the original film, released in 2005, does not have a TV series sequel. However, there is a new "Mr. & Mrs. Smith" series in development for Amazon Prime Video, starring Donald Glover and Maya Erskine. This series is set to reinterpret the story of the iconic couple but has not yet been released. Keep an eye out for updates regarding its premiere and casting details.

As of October 2023, there is no official part 2 of the movie "Mr. & Mrs. Smith." The original film, released in 2005 and starring Brad Pitt and Angelina Jolie, was a commercial success and has been discussed for a sequel over the years, but no sequel has been produced. However, there is a TV series adaptation in development, which will feature new characters and a fresh storyline inspired by the original concept. Keep an eye out for updates regarding the series!