In the context of the movie "Misery," the term refers to both the physical and emotional suffering experienced by the characters, particularly the protagonist, Paul Sheldon, who is held captive by his obsessive fan, Annie Wilkes. The film explores themes of isolation, dependency, and psychological torment, highlighting how "misery" can manifest in various forms, from physical pain to emotional anguish. The title encapsulates the intense struggles faced by Paul as he navigates his dire situation and the darker aspects of fandom and obsession.

In "Misery," Annie Wilkes exhibits symptoms consistent with obsessive-compulsive disorder (OCD) and possibly bipolar disorder. Her extreme obsession with the fictional character Paul Sheldon drives her to violent and erratic behavior when she feels threatened by his desire to escape. Additionally, her mood swings and intense emotional responses suggest elements of a personality disorder. The film portrays her as a deeply troubled individual whose mental illness leads to dangerous actions as she seeks control over Paul and her beloved novels.

James Caan and Kathy Bates had a professional relationship during the filming of "Misery." While they portrayed a tense and often hostile dynamic on screen, off-camera, they reportedly got along well. Caan appreciated Bates' dedication to her role, which earned her an Academy Award for Best Actress. However, their intense performances required a deep emotional investment, leading to a challenging working environment. Overall, their interactions were amicable, contributing to the film's success.

"Misery," directed by Rob Reiner and based on Stephen King's novel, is a psychological thriller rather than a traditional horror film. It builds tension through its intense character dynamics, focusing on the relationship between the captured author Paul Sheldon and his obsessive fan Annie Wilkes. The film's horror stems from the psychological manipulation and physical violence, creating a sense of dread and claustrophobia. While it may not feature jump scares typical of horror films, its unsettling atmosphere and strong performances make it quite disturbing and suspenseful.