Born in 1968 in St. Louis, Missouri, she is an influential American film director and screenwriter. She rose to prominence with her debut feature "Girlfight" in 2000, which won the Grand Jury Prize at Sundance. Known for her focus on strong female characters, she directed films such as "Æon Flux," "Jennifer's Body," "The Invitation," and "Destroyer." Her work often explores themes of identity and empowerment. She is also involved in television, having directed episodes for several acclaimed series.