An American actor, filmmaker, and musician, he is known for his work in the mumblecore movement. He gained recognition with roles in indie films such as "The Puffy Chair" and "Safety Not Guaranteed," and co-created the acclaimed TV series "Togetherness." He frequently collaborates with his brother, Jay, producing and directing projects under the Duplass Brothers banner. Also appearing in mainstream productions like "The Morning Show," he is celebrated for his distinctive approach to storytelling and character-driven narratives.