Born on March 26, 1972, in San Francisco, she began her career with television commercials before transitioning to film in the mid-1990s. Known for her comedic roles, she gained prominence with performances in movies like "The 40-Year-Old Virgin," "Knocked Up," and "This Is 40." Often collaborating with her husband, director Judd Apatow, she has been praised for her charm and comedic timing. Beyond acting, she supports various charitable causes and is a dedicated mother of two daughters.