An acclaimed American actor, he gained prominence with his versatile roles in television and film. He is best known for his work in TV series such as "The Larry Sanders Show" and "Arrested Development," earning praise for his comedic talent. His portrayal of a transgender woman in the series "Transparent" won him critical acclaim and multiple awards, including a Golden Globe and an Emmy. With a career spanning decades, he is recognized for his ability to blend comedy and drama seamlessly.