A Russian-born actor and comedian, he immigrated to the United States as a child. Known for his distinctive voice and surreal humor, he gained popularity in the alt-comedy scene. He is best recognized for his role as the voice of Gene Belcher on the animated television series "Bob's Burgers." Beyond acting, he has released several comedy albums and hosted "The Eugene Mirman Comedy Festival." His work spans stand-up, television, and film, often blending absurdity with wit.